Tuesday, February 22, 2011

This weekend, this blog had an abnormal spike in traffic for a 7-year-old post called "Understanding the Runner's High", something I had written when reading about early research that linked the runner's high to the endocannabinoid system (rather than the oft-quoted source of endorphins). It turns out that the New York Times ran an article this weekend with some updated findings.


 The article is an interesting read. I found the following quote particularly fascinating:
"But perhaps the most telling experiment was published last year by researchers in France who had bred mice with no functioning endocannabinoid receptors. Mice usually love to run, but the genetically modified animals, given free access to running wheels, ran about half as much as usual. Although the full intricacies of the endocannabinoid system’s role in motivating and rewarding exercise is not yet understood, it seems obvious, the researchers say, that the cannabinoid-deprived mice were not getting some necessary internal message. Typically, the endocannabinoid system “is well known to impact onto central reward networks,” the authors write. Without it, exercise seemed to provide less buzz, and the animals didn’t indulge as much."
Man, it sucks to be that mouse! But it's intriguing that a fundamental love of running could be genetically built into all of us. I've been feeling rather mouse-like on my treadmill lately and smiling the whole time. ;-)

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